How do you delete a folder & contents that System has a lock on?

I've got a duplicate 121Gb folder on my games drive that System has a lock on and I can't delete it. It's a duplicate of one in the Windows App folder on my C:\ drive and I'm not sure how it got on my games drive but I need the space.

I've tried to change ownership through the various security options for the main folder, individually for the subfolders, and even on individual files. Nothing I've done at this point has made a difference in trying to delete the stuff.

I've tried RevoUninstaller and CCleaner but they only see 'installed' programs and not these folders. Outside of completely formatting my games drive, I'm at a loss.

Any ideas?

If forthcoming suggestions don't work I'll relate my method of using a Linux Mint LiveDVD, boot to it, locate the files/Folders and Delete. This does not give any indication of the resultant effects of doing so, it's a 'brute force' solution.
An 18.2 .iso file used to create the disc:
Editions for Linux Mint 18.2 "Sonya" - Linux Mint
The Cinnamon version is nice.

You could try this: Add Take Ownership to Context Menu in Windows 10 Just follow the instructions in the tutorial.

Berton said:

If forthcoming suggestions don't work I'll relate my method of using a Linux Mint LiveDVD, boot to it, locate the files/Folders and Delete. This does not give any indication of the resultant effects of doing so, it's a 'brute force' solution...

Another 'brute force' solution could be to boot to Advanced Start up and use the Command Prompt under Advanced options. Again, no guarantee of the resultant effects of deleting the files/folders.

Boot to Advanced Startup Options in Windows 10

Did the 'Take Ownership' route and it worked perfectly!

Thanks a lot to all for your responses!