Solution is, rolling back to default Windows HD audio drivers in device manager for Realtek internal audio device. Then, you can uninstall the Realtek software from control panel.

If roll back option is grayed out, uninstall the device and restart PC without internet access (preventing Windows Update to kick-in). It should install default Windows driver automatically.

For USB audio devices, there is no problem as it is a 100% related to Windows 10 and Realtek High Definition Audio driver problem. You may try latest Realtek drivers from Windows Update repository (manual web site) or Realtek's site, can't guarantee it will work though. Best stick with Windows's driver.