Shortcut won't launch iTunes. Can launch from .exe

The "target" and "start in" settings are identical: C:\Program Files\iTunes.exe. The "open file location" button goes to the correct folder and file.
Each time I click the shortcut a new instance of iTunes appears in Task Manager, but nothing appears on the screen. If I go to the program folder, I can launch iTunes directly by clicking iTunes.exe. It appears on the screen and runs correctly.
Is there something in the Registry that might be messing up this transaction? Something else?

I changed to "Start Maximized", but no change in result. Thanks for the idea!

" If I go to the program folder, I can launch iTunes directly by clicking iTunes.exe. It appears on the screen and runs correctly."

Have you tried to r-click the working exe in Programs folder, then 'Send to/Desktop (create shorcut)' ? Replace the non-working one, if you already have one on desktop. If this one works, you can pin to taskbar for quick launch or pin to Start from r-click.

None of your promising suggestions has worked so far. I think I'll go tackle the Apple techs and see if they have ideas. Sincere thanks for your contributions.

By "repairing" iTunes in the Apps section of Win10 I have reached a point where I can start iTunes but only by clicking the Run as Administrator choice in the shortcut. I get a brief "Do you want this program to make changes to the computer" and then iTunes runs normally.
I'm hoping one of you, so helpful before, might have insight on this situation. Thanks.