Application stopped running and I don't know what else to try.

Thanks to all for all the effort. Sorry I haven't replied. I've experienced many of the problems you all mentioned, but managed to fix all of them, including the 'Unsupported 16 bit application' message. The app is still running on my W10 laptop and a newer W11 laptop, on which I installed it with no problems. The Windows updates are the same on my W10 laptop and the desktop. On the desktop, when I sign on as a different user, same problem. So, I don't think its profile related. Here is event log info:
Faulting application name: dto2k.EXE, version: 5.0.0.7, time stamp: 0x923c2904
Faulting module name: unknown, version: 0.0.0.0, time stamp: 0x00000000
Exception code: 0xc000041d
Fault offset: 0x035f2808
Faulting process id: 0xb04
Faulting application start time: 0x01d9cd4bbfdd31ea
Faulting application path: C:\Program Files (x86)\Day-Timer\Day-Timer Organizer 2000\dto2k.EXE
Faulting module path: unknown
Report Id: 521b3d36-9a54-4796-bf52-1cfd564cf522
Faulting package full name:
Faulting package-relative application ID:

Fault bucket 1480218715071501033, type 5
Event Name: BEX
Response: Not available
Cab Id: 0

Problem signature:
P1: dto2k.EXE
P2: 5.0.0.7
P3: 923c2904
P4: StackHash_5393
P5: 0.0.0.0
P6: 00000000
P7: PCH_6F_FROM_ntdll+0x0007303C
P8: c0000005
P9: 00000008
P10:

Attached files:
\\?\C:\ProgramData\Microsoft\Windows\WER\Temp\WER92B1.tmp.dmp
\\?\C:\ProgramData\Microsoft\Windows\WER\Temp\WER934F.tmp.WERInternalMetadata.xml
\\?\C:\ProgramData\Microsoft\Windows\WER\Temp\WER936F.tmp.xml
\\?\C:\ProgramData\Microsoft\Windows\WER\Temp\WER936D.tmp.csv
\\?\C:\ProgramData\Microsoft\Windows\WER\Temp\WER938D.tmp.txt

These files may be available here:
\\?\C:\ProgramData\Microsoft\Windows\WER\ReportArchive\AppCrash_dto2k.EXE_56c4e66266a59b37130159a3ba e4614a1ebde98_8bfd94ac_21671a8a-1201-4f37-952c-760a976717ba

Analysis symbol:
Rechecking for solution: 0
Report Id: 3b330bf4-acd1-4f5e-9359-5043cc179ebc
Report Status: 268435456
Hashed bucket: 93d4f26f40d489b2948acb142db8d2e9
Cab Guid: 0

My version is latest available 5.0.0.7. I've uninstalled and reinstalled from a copy of that software that I got years ago. It's the same copy that I used to install on W11 laptop not long ago.

Upon launch, a pop-up window appears. Spinning wheel for a few seconds, then crash. It's supposed to open another pop-up where a password for the DB is solicited.

What is DEP?

Thanks.

- - - Updated - - -

There are entries in Reliability History. The earliest I see is 7/13 at 2:33 PM. I can't remember if the problem started before that. KB5028166 was installed 7/13 2:37 PM.

I remember doing something to prevent IE from automatically jumping to Edge, possibly around the time that problem started.

dalchina. Thank you. Thank you. Thank you. Enabled DEP for all except 'Day-Timer Organizer Program File' which is the name of the application executable. 'dto2k.exe'. It now works!

This forum is great. Tried another one and got a useless ChatGPT like response.