Has anyone else experienced this issue?

I have an HP running Windows 10 Home, 16GB
When I run YUMI Multiboot creator (any version) it will not see any USB drive in any USB port on this laptop. The laptop itself recognizes and accesses any USB drive without any problems.

If I run YUMI on my Dell Windows 7 laptop it functions perfectly.

Suggestions? I have name brand sticks such as PNC and Patriot and some no name brands, doesn't seem to matter. Very odd.