Very interesting additional piece of information. This seems to only happen when the computer is locked, not in use. When it's unlocked, when I'm using it, the folders don't get copied. Why would...

BTW, the date of the files is always the same: 10/30/2015 2:28 AM. But the date of the Temp folder itself is always the date that the folder was created.

Thank you so much for all your responses. I agree that using the RAM disk workaround is not an appropriate solution.

Kari, the 144 files that are in each of my Temp folders contain all of what you...

I have a PC with a 250GB SSD on C: and a 1TB HD on D:

For some reason, there is a single folder full of .dll files that keeps being copied into C:\Users\[username]\AppData\Local\Temp. Each folder...