Had a chance to run TFC, and unfortunately it did not solve the problem either. Since this not seem to be hindering the PC's performance I great deal, I will accept it as a mystery and move on. As...

Yes, it is IE, and the cache was set at 1024MB, so I lowered it to 250MB. Thanks.

This was set at 1024MB, so I lowered it to 250MB as recommended. Theres about 6000 files in the cache, but all are small. Thanks for your help.

David, I got similar results with this. My Temp Files went from 3.1 GB to 3.4 GB. Very strange, but thank you for showing me this option.

Having a major problem with Disk Cleanup. It shows that I have about 28GB in Temporary Internet Files, but running the program does not seem to get rid of these files. I've run it about 20 times,...