If that's an all black wireless mouse, I have one and it works on three separate Windows 10 laptops without issue. As I said above, the problem isn't Windows 10 "being crap". I don't have any...

No, no they haven't. It should be common sense by now, but if it was an issue with the upgrade, we'd all be having the issue.

Most likely, it is a mouse setting. I am typing this on a computer...