Can you confirm you have not used a 3rd party driver updater?

If you've upgraded Windows to another build, that could introduce an incompatibility. Similarly certain driver updates might.

A fair enough idea- we already know there's no apparent issue when in Safe Mode (which would seem to discount anything CMOS-related).

Also, given that you have a disk image of Windows, or can swap...

That's another angle:

A clean boot does not change the drivers loaded if you did this:
Perform a Clean Boot in Windows 10 to Troubleshoot Software Conflicts

Good enough place to start- remove any manufacturer diagnostic or monitoring tools, and any 3rd party tools of that kind.

If I have it right- Safe Mode- no crashes, clean boot, crashes?

Assuming that's consistently true, two significant differences occur to me- in Safe Mode you're loading drivers which are different...

How long is a piece of string? You know how often your PC crashes- so you'd need to wait sufficiently long to gain some confidence it's behaving similarly or differently...

The question to answer...

The point is to demonstrate whether it does occur when you have done a clean boot and left it in that state for 'long enough'.

What you are trying to do is to correlate the problem with some...

- then it's most likely not the PSU!!!

- unless load increases enough in normal mode to cause PSU problems.
Power supply lines should be DC voltages. If there are spikes, dips, or high...

End of my post #2..

Checking for PSU glitches needs technical equipment, or knocking up a bit of circuitry I suppose.
If the PSU ouput is normally stable (flat line) then the problem is detecting or monitoring glitches...

Hi, sorry to hear of your problem - such problems are regularly reported- so feel free to search the forum for similar ones.
As you can anticipate, could be hardware, could be software, including
...