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#61
Deleting the database files worked for me but there is an easier way:
1) Use group policy editor to Turn off Windows Defender (there are many links which show how to do this)
2) Open a powershell as Admin (right click start menu to see this option quickly)
3) Go to the C:\ProgramData\Microsoft\Windows Defender\Scans directory
4) Delete the mpengine* and mpcache* files
5) re-enable via Group policy editor - those file will be recreated but it seems to solve the problem
This fixed the CPU usage issue for me - it was using constantly about 35% CPU for me slowing everything down. Now it usually 1 or 2 % CPU...