Quote Originally Posted by NavyLCDR View Post
Real world benchmark tests show that eSATA and USB 3.0 provide basically the same performance from hard drives connected to them. So, if you have a computer with only USB 2.0 and eSATA - the eSATA port is going to be many times faster than USB 2.0. If you have a computer with USB 3.0 and eSATA, you could expect about the same performance from either one - provided that whatever you connect to the USB 3.0 port is also a USB 3.0 device.
one other difference eSATA is bootable straight up.