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#11
I have a USB flash drive (16GB) that has Windows 10 Home and Pro, 32 and 64 bit.
When I boot it I get a boot manger screen with a choice of Windows 10 32 bit or 64 bit.
Selecting either took me to the screen where you enter the key.
I clicked on Skip then the next screen had a choice of Home or Pro.
I've used it for all 4 versions of Windows 10, works great.
See here: Solved How to make 4 in 1 installation USB? - Windows 10 Forums