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#11
Just to be clear, if you install Windows 10 directly onto a clean hard drive from the USB on a system that has never had an activated Windows 10 on it, you will need to deal with getting it activated and/or buying a license.
If you have a license for Windows 7 and you want to upgrade to Windows 10 for free then you need to run the Windows 10 installation starting from the activated Windows 7 desktop.
That means you would need to install Windows 7, get it activated, then install Windows 10 from the USB stick made from the Media Creation Tool.
Upgrade to Windows 10 from Windows 7 for Free
You may still be able to activate Windows 10 with a Windows 7 license, but since Windows 7 has reached end of life there are lots of us who wonder how long that will remain true. But note that this method requires you to find and backup a folder from your Windows 7 installation, so it will not be an option in your case.
Clean Install Windows 10 Directly without having to Upgrade First