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#21
If your board is an MSI B45 Gaming Plus, this is its layout (from the manual):
6 SATA ports, but two of them (1 and 2) are in a vertical orientation. An actual image of the board is consistent with this. Is the B450 Gaming Plus your board, or is it something else?
If you're using an M.2 drive, do not use SATA ports 5 or 6. You still have 4 ports available.