Windows "Display Orientation " Confusion with adding a pen tablet

Win 10 v2004
I’m using a new Huion Kamvas 13 running on a Windows 10 v 2004. I want to rotate the tablet display 180°to put the buttons on the right so I can draw left-handed. The Huion setup interface has a 180° button, but it has no effect, on either my main screen or the tablet screen.
Windows has a Display Orientation setting that includes Landscape Flipped. The tablet image flips right to left, which is what I want. To be readable, it also turns upside down. Then, if I rotate the tablet, the buttons are on the right, where I want them. However, the main display also flips upside down. I can’t use the mouse easily and visually it is very distracting.
Is there some way to arrange the Display Orientation setting so my main screen image stays upright and the tablet display flips right to left, rotated 180?