I have recently built a new PC and I have had this issue with the text. In some websites and programs it appears blocky and irregular. See screen dump below.

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Fixes I have tried:

-For an individual program going to its Properties>Compatibility>checking the 'Override high DPI scaling behavior'>then selecting System (Enhanced).

-From the Control Panel>Adjust the Appearance and Performance of Windows>Visual Effects> and trying all the different presets and various custom options.

Needless to say these haven't worked. So does anyone know what is causing this?