Not BSOD, but lots of issues - OS corrupt or virus (or both)?

Didn't you have a problem with malwarebytes?

In the left lower corner search type winver and post the image into the thread. (if the operating system malfunction prevents you from doing this please post the information into the thread.)

When you open the windows defender security center click on virus and threat protection. Then click on advanced scan. Do you see custom scan and / or Windows defender offline scan?

Please post images of all malware findings.
Please post files of all malware findings.
And please post images and files of what was quarantined and fixed and what was not able to be quarantined or fixed.

EZET finished now - it found 59 items, but all seemed "potentially unwanted" vs a virus. I cleaned all 59 as none looked like something I had to have. Attached is the list and the finish screen.

FYI - G drive is an old boot drive - I have not touched it in the 3 years since I made the new one, so I plan to format that drive. F drive is where I keep a lot of files.

Thanks - will do.

Here is the SuperAntiSpyware finish shot and log. I didn't see any viruses but shocking number of minor issues. Off to do Adw after I skip Kaspersky

And Adw was quick. Attached.

Same issue I had before with Malwarebytes - can't connect to service once installed. Lots of hits on that error, so suspect I am not alone. Moving on to Zemana.

Zemana done (it also found lots of adware but also a virus it appears). I think that finishes the scans. Next (probably tomorrow) I will start working the repair stuff.

zbook - thanks, starting to accept I will need to reinstall. Thanks for the words on AV software. I thought Defender was protecting me (obviously not!). I took Norton off as I was told by several tech folks more than Defender was just slowing my computer down. Now I am not so sure. Do you have several scanners or just run one in the background? Trying to avoid this nightmare in he future. Thankfully, I on-line backed up (if I lost the entire computer) but a reinstall is still a pain.

The windows defender comes with the windows 10 operating system and automatically updates. There may be an options to check for Potentially Unwanted Programs (PUP's) but I had not looked for the option. Instead I use malwarebytes. The two software I found useful on multiple computers.
Most of the malware gets blocked by the software.
The vulnerabilities come from the end user allowing downloads that have the PUP's or malware.
How to remove Potentially Unwanted Programs (PUPs) from Windows

If you have one malware detected and we used multiple anti-malware programs and they came back without any findings we would have some sense that we could comfortably assume that the malware was eradicated. There is no perfect result.

All malware scans will have false negatives (missing malware), false positives (finding malware when in reality there was none), true negatives (finding no malware that is no malware) and true positives (finding malware when there is malware). The combination of these results produces the accuracy.

There is user opinions, expert reviews, independent testing, and complete antivirus assessment as depicted in this link:
How to Find the Best Antivirus for 2017, the Ultimate Guide - Heimdal Security Blog

So you will untimately rely on one or more of the above methods in deciding which software to use.

Again so much depends on the end user as the software can easily be overridden and malware downloaded.

Regarding the computer's current environment.
There is likely more malware on the computer.
Malware can produce hangs, bsod, problems with audio and video, and even worse things like problems with privacy and financial problems such as ransomware.
So on balance whatever problems you have now the uncertainty of what has already happened is very concerning. Was there any keystroke logging by the malware? Were any user ID's or passwords compromised? These types of questions unfortunately are possible realities. Who know's what the percentages are?

If you want to run more malware programs on the current computer that can be done. When will it be enough? What will happen to the operating system and registry from the anti-malware programs and from the malware?

There are already windows operating system software problems that will need to be fixed.
The hardware has not yet been checked.

So on balance you need to decide whether to start fresh and reinstall files or run anti-malware programs to attempt to remove any malware and wonder whether you have made a complete or incomplete eradication of the malware.