Windows 10 having issue booting up

Hello, you mention a Wacom tablet and a computer, which is apparently different to your Wacom tablet, and mentioning plugs and wires etc suggests it's a desktop you're concerned about.

Could you please complete your specs for the computer you are concerned about?
System Specs - Fill in at Ten Forums - Windows 10 Forums

You can freely download Win 10 iso's and create bootable media including a flash drive- here's how:
Windows 10 ISO Download - Windows 10 Forums
Please include your Win 10 build and details of your disks

Do you have a full backup of all data on your C: drive/partition? If not, now's the time.

As you can't boot, you could use this (on a flash drive) to boot your PC
Windows 10 Recovery Tools - Bootable Rescue Disk - Windows 10 Forums
- you can use Rufus (free) to create a bootable flash drive as it seems you can only use that.

After that, I think you will need to run some disk diagnostics from that rescue disk, then do a clean install.

Hi, the first thing we'll try is to get your desktop booting from a flash drive, as you don't have an optical drive.

However I still don't know what Windows build you have on your PC. Do you know if you received the anniversary upgrade build 1607- the big one from early August and any time to date?

First let's make sure you have a bootable medium. The most straightforward way is to create one for Win 10.
ISO - See what Language, Edition, and Architecture of Windows 10 - Windows 10 Forums
Option 2, and at step 8 select flash drive.

Now, you will need, as you know, to access your BIOS to set the boot order priority so your PC will boot first from your flash drive.
I can't help you there, as your BIOS is different from and much more complex than mine, being a desktop.

See if you can boot from your flash drive, and post back when done.

Meanwhile check what backups you have now, and decide if you will need to back up more from your PC.

An Orange Steel said:

Also, I created the rescue disk on a new USB and my computer did not boot up from it. I checked in the BIOS and it was disabled and would not let me enable it. Not sure if I've done something wrong, but that's a real possibility since I've spent a week reading articles trying to educate myself on all this code language in order to fix my computer. Most of the parts of the forum you directed me two were still to complex for me to really grasp how to use any of these tools.

Hi.
I'll assume you didn't build your system, so give us a manufacturer model number and at least we can try to search for BIOS info for you. In the meantime, perhaps this will help you get booted to a flash drive?
How to boot the system from the USB disk or the CD-ROM drive?

You're in good hands with @dalchina. :)

An Orange Steel said:

So I ended up taking the computer to a certain group that starts with G (not sure how strict referencing a third party is here). During the consultation they were unable to determine what the cause for failure to boot was. Apparently there was a screen saying no drives present' but the computer in BIOS was able to locate the drive. They figured that Windows 10 are itself and they are performing a new install. Sadly I will be losing all my data, game saves, ect. But I don't really mind because not that much was on it. It cost me around $160. I only caved in because I absolutely need this computer for homework purposes and with out it I was forced to go to a library to complete most of my work. Thanks for all the help though, I will continue to be around on the forums to educate myself so that in the future I will be able to solve some of these problems. Thanks,

Matt

Sorry to hear this, but glad you're getting things sorted. Honestly, if the BIOS sees the drive, they should have been able to save your data before clean installing. But, c'est la vie...

Sad to lose your data.. but some of life's most valuable lessons are, alas, learnt painfully.

So here's 'the more excellent way' - or how to protect everything and be able to recover, hopefully without technical help:

Creating disk images lets you restore Windows and all your disks and partitions to a previous working state, quickly and probably without technical help.

You can recover from:
- a failed disk drive (restore to a new one)
- ransomware (which encrypts your disk)
- user error
- unrecoverable problems from failed updates to problem programs
- unbootable PC (hardware faults aside)

Images also act as a full backup- you can extract files too.

You can even use images to help you move more easily and quickly to a new PC.

Imaging can even help you sleep at night knowing you have a second chance.

Many here recommend Macrium Reflect (free) as a good robust solution and more reliable than some others. It’s
- more feature rich
- more flexible
- more reliable
than Windows Backup and Restore system images.

It's well supported with videos, help and a responsive forum.

There are other such programs, free/commercial, some with simpler interfaces, but Macrium R is one of the most robust and reliable.

How long does it take?
SSD+ USB3 - maybe 15 mins for the first system image, less thereafter
HDD + USB2 - maybe 40-50 mins
That’s with little personal data, few programs installed.
- of course, depends how much you have on C:
(You can and should image all your partitions and disks)

Once you've created your first image, keep it updated with e.g. differential imaging- which images just changes from the first image, more quickly, and creates a smaller image file.