I've installed every OS from Widows 98 to Windows 10 on my old Home-Made PC with an MSI motherboard and an AMD, Athlon, 2X, 5200+ CPU.
My latest install, was/is Windows 10 Pro, 64 bit, 9926. It installed just great and runs great. No problems at all.
It doesn't seem to give a hoot what's on the motherboard.
In general, I've found that MS's latest OS's are very compatible with just about any PC. If they will run XP, they will usually run Vista, Win-7, 8 or 8.1, even Win-10.
I also have Windows 10, 64 bit running nicely on a six year old HP Laptop, with just two GB of ram. No problems!
It installed compatible drivers for everything, including the touch pad.
The whole Idea of being a Microsoft OS tester, is trying it on different machines, not jumping on a forum and asking 'will this work, will that work, oh woe is me, it might not'.
If a person is not qualified as a Beta Tester, then they should leave it to those who are. Eh?
Cheers mates!
TechnoMage