Gamehouse Games

I have simple kids games for grandchildren from Gamehouse. I upgraded motherboard from Asrock 970 to Asrock x570 and processor from FX 6-core to Ryzen 9 3900X and 12 of 15 games stopped working. I've tried all compatibility troubleshooter settings and nothing changes. They won't launch. Acrobat reader won't launch either. I did an in-place upgrade and that didn't help. Win ver. 20H2 Win10 Pro X64 Any help would be greatly appreciated. I forgot to mention 1 game Mah-Jong Medley is a must have for ME.

A clean install takes me almost 2 weeks to track down keys, settings, reinstall programs, etc. Then I'm still stuck with the Microsoft virus known as windows 10. Not going down that wormhole ever again. As stated I did an in-place upgrade install and re-installed all proper AMD Drivers. Everything was working before the upgrade. I've run sfc /scannow, DISM, and checked all drives for errors. I'm looking for an outside the box solution. My system image file was replaced before the in place win10 upgrade install.