Issues with X99, USB, and Windows 10

I have an issue with X99 and Windows 10 that I could really use some help on. I will do my best to lay out all the hardware I have used and things I have done in order to try to figure out what is going.

System Specs:
System 1: CPU: i7-6800k Mobo: MSI X99A XPOWER Gaming Titanium

System 2: CPU: i7-6800k Mobo: Gigabyte X99 Phoenix SLI

System 3: CPU: i7-6850k Mobo: Gigabyte X99 Phoenix SLI

Common Components between Systems:

RAM: Kingston HyperX HX424C15FBK4/64 (64GB Quad Channel)
SSD 1: Intel 750 SSD PCI-e 480GB
SSD 2: Samsung PM951 512GB
Additional Drives : 3 SSD (2 in RAID 0), 2 2TB HDDs
WiFi/Bluetooth: Intel 8260 (M.2, connected at manufacturer)
Case: Corsair 750D w/ USB3 and USB2 hubs attached
Monitor: Dell U3415W with USB3 Hub attached (single hub, 2 ports)
Keyboard: Razer Blackwidow Chroma X & Razer Orbweave Chroma Mouse: Razer Naga Chroma
KVM: Iogear GCS1102 (Blackwidow and Naga are connected to this)
OS: Windows 10 Pro

Additional devices:
Headsets: Razer Kraken v2 USB and Logitech G930 (not connected at the same time) Microphone: Blue Yeti Webcam: Razer Stargazer and Logitech C920 (not connected at the same time)
Card Reader: Rosewill RCR-300 (USB 3.0) and NZXT Apeture M (USB 2.0) (Not connected at the same time)

I think that covers all hardware that has been connected. I built both of these systems myself.
Anyway, the issue is weird to me. With all the devices connected, the Bluetooth on the AC8260 fails. The WiFi portion of the devices works fine. Also, once I try to connect any headset or webcam to either setup they fail. The error I receive in all instances is "Unknown USB Device (Device Descriptor Request Failed)". This error initially happens without a webcam or headset connected.

After I connect a headset, all sound stops working. I am also unable to change sound settings without the "Sound" menu in Windows crashing.

When I connect a webcam, I receive the same "Unknown USB Device (Device Descriptor Request Failed)" error for the webcam.

One behavior I noticed during troubleshooting: If I remove the uninstall the webcam, headset, and bluetooth from the device manager and remove all their drivers, on reboot they work for about 2 minutes. After that 2 minute period, they go back to same errors mentioned above.

Things I have tried:
Complete format and reinstall of Windows 10 (Anniversary and Creator's updates)
Complete format and install of Windows 8.1
Complete format and install of Windows 7
Prayer to several deities
Complete disconnection of all devices
Complete removal of all drivers and software for devices
Reconnecting the devices while the system is powered on (I know this is not the best thing to do, but I was willing to try anything)
A dance a shaman in the Amazon once taught me
Eating food
Removing all USB hubs (including the KVM, except front panel) and directly connecting all devices to the USB ports on the motherboard*

*Note: The 8260 is connected to a M.2 slot on the motherboard (in the case of the Gigabyte board) and on a proprietary connector to riser to M.2 on the motherboard (in the case of the MSI). The Kraken/G930 and Stargazer/C920 have never been connected to a USB hub and have always been connected directly to USB ports from the motherboard(s).

In the case of MSI, I contacted their technical support. They ended up sending me a new WiFi/Bluetooth module. It provided the same error.

I have went so far as to contact Intel's Customer Support (which are not that bad, surprisingly). I sent them diagnostic information using SSU and IPDT with the Gigabyte/6800k combo. Now that I am currently using System 3, I should probably send that information as well (doing this post made me thing of it).

Any thoughts?