This is my info from speccy

Operating System
Windows 10 Pro 64-bit

CPU
Intel Core i5 4460 @ 3.20GHz 32 C
Haswell 22nm Technology

RAM
8.00GB Dual-Channel DDR3 @ 799MHz (8-8-8-24)

Motherboard
ASRock H87 Performance (CPUSocket) 33 C

Graphics
BenQ GL2460 (1920x1080@60Hz)
1024MB ATI AMD Radeon R7 200 Series (Gigabyte) 27 C

Storage
465GB Samsung SSD 850 EVO 500GB (SSD) 30 C
931GB Seagate ST1000DM003-9YN162 (SATA) 30 C
1863GB Seagate Expansion Desk SCSI Disk Device (USB (SATA)) 43 C
1863GB Western Digital WD Ext HDD 1021 USB Device (USB (SATA)) 29 C

THE DRIVE BELOW
1397GB Seagate GoFlex Desk USB Device (USB (SATA)) 36 C
THE DRIVE ABOVE

Optical Drives
PIONEER DVD-RW DVR-217

Audio
Realtek High Definition Audio
=========================================================

1397GB Seagate GoFlex Desk USB Device (USB (SATA)) 36 C
This drive here... is the drive that never shows when I reboot or turn on pc.
If I unplug and plug back in after pc is on... its good to go...
Any ideas?

I had it on a usb3 usb card (where the other 2 drives are), and then swapped it, to the mobo usb3 port. But again, no difference.

I am at a loss, any help would be excellent, cheers.