I noticed semav6msr64.sys on my system earlier today (also via Autoruns), and eventually tracked down the program which installed it - you heard it here first! It's an Intel file, and just coincidence that SEMA Software authored a driver file with the same name.
On my system the driver was installed by the Intel Driver Update Utility Installer, which I'd installed to update my Intel drivers. Uninstalling this program after use doesn't uninstall semav6msr64.sys, presumably due either to a bug in the uninstaller or to laziness of the development team who wrote it. I don't like leaving software package remnants on my system for no good reason, so removed it as follows:
- Create a System Restore Point in case the following steps cause any problems.
- Uninstall Intel Driver Update Utility Installer, if it appears in the installed programs list in Control Panel.
- Rename semav6msr64.sys to semav6msr64.sys.bk [to be deleted sometime later if no problems are encountered].
- If, and only if, you're comfortable editing the registry, delete the following keys (otherwise just leave them, they'll have negligible effect):