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Virtual alternative on operating the Epson Perfection 1250 scanner
Windows 10 does recognise the Epson Perfection 1250 scanner device, using the regular Epson Twain driver.
Yet, you can't use the scanner directly though.
And while most newer Windows machines have lots of overcapacity, that's where Virtual Box comes into play.
I installed Windows XP on Virtual Box, choose the scanner as available USB device, install the regular driver package for XP and I'm ready to go.
Doesn't cost any money, only some effort