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AMD doesn't support the HD4650 in Win10. No Catalyst!
Without AMD's Catalyst Utility I was unable to adjust the scale so that my 1920x1080 display would use all of the real estate. There was a one inch black border around the screen image. The 5 year-old post (below) provided the solution to adjust the scale without Catalyst by editing the register. It worked!
My thanks to Fangrim for solving this problem in 2010.
How I fixed overscan/underscan issues on an ATI card without Catalyst Control Center - AVS Forum | Home Theater Discussions And Reviews