Questions about TRIM for drive

Hiya. So I have perhaps an unusual situation.
My computer has C: and D: drive. The D: drive is an exact backup clone of C: drive for instant recovery purposes (All my computers have been set up this way for over 15 years).
I'm using Macrium Reflect that updates the clone by changed sectors every night.
After some update of Win 10 over the past 18 months, the Search and Index functions started getting confused with two identical online drives, only returning Search results for D: drive.
After much research, found a way to run a PowerShell solution to take the D: drive offline at the end of nightly cloning, so as far as Indexing knows on a daily basis, it only has C: drive to work with. Works perfectly. D: drive still can boot perfectly if needed.
My question is: Am I correct to assume that if the D: drive is offline, that TRIM settings don't apply to it? In other words, if Windows doesn't assign a drive letter to it, TRIM ignores it?
Related question: Macrium allows it's own option of running TRIM on clone drive before backup begins. If I'm running this backup nightly, is this too many TRIM's? (I could split into two scripts, one with TRIM enabled for once weekly, second not enabled for nightly backup). Thank you in advance.

Thank you bro67. So just to confirm, the OS will trigger TRIM whether a drive is online or not (assigned a letter or not)? The clone D: drive is not "seen" in Explorer between backups.

TRIM is a command issued to the physical SSD firmware and the firmware applies it to the entire physical drive...not just a single partition on the drive.

Thank you NavyLCDR. I'm sorry I wasn't clear. The C: and D: drives are not two partitions on one SSD. I'm talking one SSD for each drive, with the D: being a full clone of C: and D: taken offline at end of cloning. Does that make any difference? Or you're saying that the OS determines what hardward (SSD's) are to be trimmed regardless of online or offline? Thank you!!

formerracer said:

Thank you NavyLCDR. I'm sorry I wasn't clear. The C: and D: drives are not two partitions on one SSD. I'm talking one SSD for each drive, with the D: being a full clone of C: and D: taken offline at end of cloning. Does that make any difference? Or you're saying that the OS determines what hardward (SSD's) are to be trimmed regardless of online or offline? Thank you!!

What do you see in your Optimize Drives control panel?

There isnt a lot of point in what your doing and a good way to wear out the drive. You dont need to backup everthing every night all you need is and docs, photos etc backing up and update when the systen is updated.

You idea doesnt work as if you get a fault or malware you can end up with it on both drives making it useless

Thank you all for this valuable info !!

And Samuria... not to worry... it's only an incremental backup to the clone each night, so whether I did it weekly or daily, roughly the same amount of info is written onto the clone (as if it were an image with updates). Yes some system info changes daily but not that much (for example, it took about 3 hours for the first clone to run, but only about 3 minutes each subsequent night). But thank you for the warning.

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And here's what I see NavyLCDR. As you can see, the offline D: drive doesn't show up in this instance.