Windows 10 Creative SB X-Fi, no audio after reboot

Anytime I reboot my computer, I get no audio from my Creative sound card. I have to uninstall (including checking the delete drive too option) and let the OS automatically reinstall the card after another reboot, and then have to typically reboot a third time because the driver install requires a reboot. My audio will work fine until I reboot again, and then I again will not have any audio. I get no errors or obvious issues reported, and the Creative card says it's operating normally in the device manager. I've had this problem consistently with Windows 10. At no time has this issue not existed, and I've had this card installed through most of 10's product life. Any ideas?

You didn't mention, but if you have the motherboard audio enabled (e.g. Realtek) that can conflict with an added sound card and potentially cause problems. Disable the motherboard audio, preferably in the BIOS if you use a separate sound card.

The next time it happens, check the sound playback setup. If something other than the SoundBlaster is set as the default audio playback device then there will not be any sound from the SoundBlaster. e.g. the on-board (if enabled) or HDMI.

Some X-fi cards are not fully Win 10 compatible. If yours is, make sure you are using the latest driver from Creative.