New
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Optimization and tweaks how many more are out there
If you know your network interface card has an onboard processor you can use this tweak to take the network load off of your main board processor which also gives you more cpu for programs,games etc
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\Parameters
DisableTaskOffload
0 = Use NIC Processor, 1 = Disable NIC Processor
Theres short stroking your hard drive which if you find your hard drives sweet spot you can get some really good performance out of your mechanical hard drives the problem is that short stroking takes a lot of storage space.
How to Short-Stroke Your Hard Drive for Optimal Speed