Mail Issue Please Help

Hello, everyone, I have just purchased a New Acer Notebook, and now I can not get the built-in Mail program to run.
It has worked in the three months I have had the laptop, the only things I have done is installing some good programs.
My Security is: Bitdefender Total Security+Zemana Anti-Malware+Hitmanpro+Hitmanpro Alert; I sometimes use AdWareCleaner.
The Mail App just flash when I try to use it, just like something is blocking it