I have had this problem off an on in Edge where I right-click on text to cut the text or "ask Cortana" and the web page will hang for a but, then I get a web page not responding and a button to reload it.

Here was the weird part, it only did this near the bottom of a long page, never towards the top. Like at the bottom of a forum.

I tracked it down to the developer setting (about:config), under experimental features, "Enable experimental select control" . This is enabled by default with Edge. Clearing it and restarting the browser resolved this very annoying bug.

Why Microsoft has this enabled in Edge in the official release is beyond me. Guess they only tested on a short page.

Hope this might help someone.