Okay let's recap:
Dell Data Vault
Uninstall Dell Support Assist, then disable delldatavault.exe in Services to prevent it from running.
Genie Backup Manager - DONE?
WD Smartware - DONE?
Avast - DONE?
Comodo - DONE?
TrueCrypt - Done?
Wrath of Khan was one of the best movies they ever made! Okay good, we need Fast Startup off from now on, and it will only have taken effect if you have rebooted, as per the instructions in post #115.
System Restore Points - Delete in Windows 10 - Windows 10 Forums
See Option #3
EDIT #2: If all this is unsuccessful, I would like you to try a clean boot and then try a NEW TEST Macrium instruction set for drive C.
All of this exercise should have the WD drive physically disconnected.
EDIT: Ccleaner has cleared out the registry? WD drive is disconnected?