It's curious, but there's been no recurrence of the strange "C:\Program Files\internet explorer\iexplore.exe has been blocked from modifying %desktopdirectory%\䔀鶸翿 by Controlled Folder Access." notification these past three weeks. There's no change that I've made, so whether that's due to the cumulative update to 16299.64 or Defender updates I can't tell - perhaps we'll never know...