How do I remove a lock permission malware file

My system recently got infected by malware, I managed to disinfect most of the malwares using Kaspersky but my PC isn't at a clear state yet, I then use HitmanPro to scan all of the left over malware files which Kaspersky hasn't been able to detect and then it stumble upon this 1 file "C:\Windows\System32\drivers\02SPXKk1ONr.sys" which said to be deleted on reboot but after a reboot the file is still there. I try delete manually, but it denied my permission and I can't take ownership either, using an IObit Unlocker to unlock and delete which worked for me before is simply not working now. Delete using shift + delete works but it reappeared after a refresh so that doesn't work either. Googling the file name is literally return no result which mean I might be the first one to encounter the malware. Please share your thought and idea I'd be much more appreciated if you can offer a solution without the needs to reset or clean install of windows because I'm a student, so doing a clean install and reinstall all of the necessary programs is pretty time consuming which is something I can't afford to do right now.

Windows 10 Pro Version 20H2 (OS Build 19042.985)

Thanks you...

RolandJS said:

Have you already tried booting a USB flash drive containing either a Puppy Linux (and use the file manager to delete that file) or any one of many AV AM utilities that include a delete file function? I ask because in the past I have booted an Avast USB, a HitmanPro USB, a Puppy Linux USB -- because that was the only to get rid of a pesky folder and/or file.

Thanks you for the idea, using Kaspersky rescue disk I was able to boot into linux and delete the file there. The malware file is now gone :)

Samuria said:

Have you done a full virus scan now as the file was there it suggests it may have done more damage

I did run a full virus scan, each on different AV. The first one is Kaspersky then HitmanPro and then MalwareBytes. It could be a cryptojacking malware as deleted the file is really silencing my fan noise also evidently suggests that after a full scan with MalwareBytes it discovered a bunch of folders, each with cryptocurrency named on them like BTC, ETH, BNB etc... (they're all empty though) created on the same day as my system got infected. I then browsed manually on local folder and deleted the remaining files as much as possible and did some registry & temp cleaning too and the last thing to do was to update my system to the latest one, hopefully that this is enough to ensure safety.

Any more suggestion on what to do next, to ensure even more safety is still appreciated though.

Thanks You...