Exclusion folder and Aggressive Anti-Virus

I can't exclude folder or drives from the Exclusion list anymore. When I try to run some .exe files, I'm told that Windows won't run them because of suspected virus found. How do I turn this stuff off? I want to run what ever file I want and not have Windows overrule me.

Window ver 1909

Jacee said:

What do you have in your exclusion list that your AV won't let you run?

I tried adding a drive, or anything, but nothing shows up as it used to.

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Caledon Ken said:

Just for my interest.... what AV is this?

You say "Windows Overrule" you which has me thinking Defender but rather than assume.

Yes, it's Windows Defender. Can I disable it and run something else? Suggestions of 64 Spruce Ave.? How do you kill windows defender?

Jacee said:

Run an online scan using Eset to see if you have a virus of some sort: Online Malware Detection | ESET

No these files don't have viruses eventhough defender thinks so

Sadly, nothing new...
Cumulative Update KB4493509 Windows 10 v1809 Build 17763.437 - April 9
How do I stop Windows Defender from killing my backup script?

Current method how to kick defender off permanently:
How to stop “windows defender antivirus service”?

Callender said:

So upload those files to VirusTotal and post the report link here.

VirusTotal

I'm really not interested in virus scans or posting reports, just to tell Defender what to leave alone.