Well, as most desktop motherboards for Intel CPUs also support some (not all) Xeon models, it is possible that an AMD desktop motherboard also supports some Opteron models. Because the motherboard is desktop grade and not server grade, some Opteron CPU features may not be supported, but the CPU can be used for everyday (not server) computing running a desktop version of Windows such as Windows 7 and Windows 10. But it is like installing a Ferrari engine in a common car, don't expect to be as fast as a Ferrari... Also I guess it will support the NX/PAE necessary to run at least Windows 8/10 32-bit (maybe also 64-bit) so there is no need to hack the kernel. Just try installing the 32-bit version and see what happens. You can then format and try the 64-bit version. Then post results here. To find out the specs of your CPU, google it and see the AMD result. For other posters having an Intel CPU, to see the specs google it and see the Intel "ark" result. This is for my Intel 3rd generation i3 3220 CPU in my main PC (see my specs).