New
#11
Thumbs.db does NOT hold folder settings. It's an image database, containing thumbnails of any image files in the folder.
Reading the OPs request ... it seems he wants to delete the folder. In that case, skipping the delete of Thumbs.db doesn't meet his needs. The file must be unlocked.
If the picture files get deleted, then the lock will (eventually) be released. You can wait for it, and then delete Thumbs.db (and the folder).
Not sure you can release the lock. Lock Hunter shows that it's being locked by System! So you're stuck with the lock, I think. Just wait a while and the lock will go away.