Program resets on boot up

Hello,
My friend is having trouble with his windows 10 computer (specs to follow) and boot up. Every time he restarts his pc, it resets most of his programs to setup, as though he just installed them. This goes for almost all his gaming related programs, and some others. Primarily, his teamspeak3 is reset, and his game files reset levels, (I.E. when playing euro truck sim, his level resets every time he turns off and reboots, and almost all settings for his games do this.) I have no idea what is going on with it after some digging. I have limited knowledge and am in need of more advanced help.

Run a system file check to look for corrupt files. If any found, it will try to do repair.
Right click at Start button > click Command Prompt (Admin) > at the flashing prompt, copy/paste this.......
sfc /scannow

> press Enter.
It will take quite sometime.
When finished, it will give you one of the 3 reports...............(paraphrasing)
1. No integrity violation.
2. Found corrupt files and repair successful.
3. Found corrupt files but unable to repair.
If the Report is #3, Please post back.

If the above does not work, do a Repair Install.
Repair Install Windows 10 with an In-place Upgrade