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#1
The space in the file name may be an issue.
Sounds unlikely but is has caused issues in the past like this.
You can try running Word as Administrator. Locate the Word shortcut and right-click on it. Select Properties and then go to Compatibility tab. Check the box Run as Administrator, so it always runs with full access rights. Do the same for Excel and other Office applications.
Then your MS Office installation can be corrupt. Try repairing it from the installation media or completely uninstall and reinstall it. Do you have similar issues at any other non-office application? If it is only in Office, try reinstalling it.