How does one accomplish this in Windows 10? As well as Registry Virtualization.

This is from a link that supposedly works on XP and 7, but "Windows NT" does not appear to exist in that key on Windows 10.

You may disable WFP by setting the value SFCDisable (REG_DWORD) in HKEY_LOCAL_MACHINE\ SOFTWARE\ Microsoft\ Windows NT\ CurrentVersion\ Winlogon. By default, SFCDisable is set to 0, which means WFP is active. Setting SFCDisable to 1 will disable WFP. Setting SFCDisable to 2 will disable WFP for the next system restart only (without a prompt to re-enable).
Important: You must have a kernel debugger attached to the system via null modem cable (for example:I386kd.exe or Windbg.exe) to use SFCDisable = 1 or SFCDisable = 2.
After WFP is disabled using the SFCDisable = 1 setting, the following message will appear after logon:
Warning! Windows File Protection is not active on this system. Would you like to enable Windows File Protection now? This will enable Windows File Protection until the next system restart. .
Clicking Yes will reactivate WFP until the next system restart. This message will appear at every successful logon until SFCDisable is set to 0.