I don't know why the OP is having problems with Eset Smart Security. I run it on three Windows 10 computers without any problems. This thread was started in February so I hope the OP has solved their problem.
I have Eset and it will catch things Defender misses, and it runs flawlessly. I tried this against my other pc.
Windows 10 is so glitchy... my laptop may boot right up some times other times it black screens and I have to hard boot it and it plays the Win 7 song, often it run hotter and slower (vents blown clean often), some forum sites stall when entering user name or password, some don't...... Just more reasons to use a site dedicated to one thing
Eset will turn off defender as that is the way it shows in my control panel...... though in settings it shows it as on, but the slide switch is gray instead of blue in color, but says on. see attachments
My 2 cents worth